Mal-amido-PEG2-acid

Name: Mal-amido-PEG2-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 756525-98-1

Cat No.: BPG-1969

Purity: >97%

4.5

Mal-amido-PEG2-acid is a maleimide-functionalized ADC linker enabling site-specific antibody conjugation with enhanced stability and optimized payload attachment for improved targeted therapy outcomes.

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C14H20N2O7
Molecular Weight	328.32
Appearance	White Solid
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, stored under nitrogen; In solvent, -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Structure of 756525-98-1

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Mal-amido-PEG2-C2-acid; 3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid
IUPACName	3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoic acid
CanonicalSMILES	C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCC(=O)O
InChI	InChI=1S/C14H20N2O7/c17-11(3-6-16-12(18)1-2-13(16)19)15-5-8-23-10-9-22-7-4-14(20)21/h1-2H,3-10H2,(H,15,17)(H,20,21)
InChIKey	GBPJQBDDYXDSNH-UHFFFAOYSA-N
BoilingPoint	617.3±55.0 °C at 760 mmHg
Purity	>97%
Density	1.3±0.1 g/cm3
ExactMass	328.12705098
LogP	-0.74560

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Primary Amines (after activation)
ReactionChemistry	Maleimide-Thiol Conjugation; Carbodiimide-Mediated Amide Coupling (EDC/NHS)
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Thiol-Selective Biomolecule Conjugation; Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation