| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C30H55NO15 |
| Molecular Weight | 669.76 |
| Appearance | Liquid |
| Storage | Store at -20°C |
Mal-amido-PEG12-aldehyde
Mal-amido-PEG12-aldehyde is a heterobifunctional PEG linker containing a maleimide group and an aldehyde group. The maleimide group can react with the thiol group in biomolecules, and the aldehyde is an amine-reactive group that can form conjugates with proteins and peptides.
Structure of Mal-amido-PEG12-aldehyde
Ordering Information
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | Maleimide-NH-PEG12-aldehyde; Mal-NH-PEG12-aldehyde |
| PEGType | Discrete PEG Linker |
| PEGArchitecture | Linear |
| Functionality | Heterobifunctional |
| ReactiveToward | Thiols; Aminooxy Groups; Hydrazides / Hydrazines; Primary Amines |
| ReactionChemistry | Maleimide-Thiol Conjugation; Oxime Ligation; Hydrazone Formation; Reductive Amination |
| BiomoleculeCompatibility | Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Carbonyl-Reactive Proteins / Peptides; Glycans / Oxidized Glycoproteins; Aminooxy- or Hydrazide-Modified Oligonucleotides |
| ResearchUse | Thiol-Selective Biomolecule Conjugation; Carbonyl–Aminooxy Oxime Ligation; Carbonyl–Hydrazide Ligation |
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