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Mal-amido-PEG12-aldehyde

Cat No. Cat No.: BPG-2457
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Mal-amido-PEG12-aldehyde is a heterobifunctional PEG linker containing a maleimide group and an aldehyde group. The maleimide group can react with the thiol group in biomolecules, and the aldehyde is an amine-reactive group that can form conjugates with proteins and peptides.

Category Small-molecule Heterobifunctional PEG
Molecular Formula C30H55NO15
Molecular Weight 669.76
Appearance Liquid
Storage Store at -20°C
Mal-amido-PEG12-aldehyde

Structure of Mal-amido-PEG12-aldehyde

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  • Specification
  • Key Product Attributes
  • Reaction & Conjugation Properties
Synonyms Maleimide-NH-PEG12-aldehyde; Mal-NH-PEG12-aldehyde
PEGType Discrete PEG Linker
PEGArchitecture Linear
Functionality Heterobifunctional
ReactiveToward Thiols; Aminooxy Groups; Hydrazides / Hydrazines; Primary Amines
ReactionChemistry Maleimide-Thiol Conjugation; Oxime Ligation; Hydrazone Formation; Reductive Amination
BiomoleculeCompatibility Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Carbonyl-Reactive Proteins / Peptides; Glycans / Oxidized Glycoproteins; Aminooxy- or Hydrazide-Modified Oligonucleotides
ResearchUse Thiol-Selective Biomolecule Conjugation; Carbonyl–Aminooxy Oxime Ligation; Carbonyl–Hydrazide Ligation

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