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Hydroxy-PEG7-t-butyl acetate

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Category Small-molecule Group Protected PEG
Catalog NO. BPG-2160
Product Name Hydroxy-PEG7-t-butyl acetate
Molecular Formula C20H40O10
Molecular Weight 440.53
Hydroxy-PEG7-t-butyl acetate
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Product Information

Description Hydroxy-PEG7-t-butyl acetate is a PEG linker containing a tert-butyl acetate. The carboxyl group is protected by the tert-butyl group.
Synonyms HO-PEG7-CH2COOtBu
Purity >95%
Appearance Transparent Liquid
Storage Store at -20°C

Hydroxy-PEG7-t-butyl acetate, a versatile compound with unique chemical properties, finds diverse applications in bioconjugation and drug delivery systems. Here are four key applications presented with high perplexity and burstiness:

Drug Delivery Systems: Through the modification of drug molecules, Hydroxy-PEG7-t-butyl acetate enhances their solubility and stability. By conjugating this compound to therapeutic agents, researchers optimize pharmacokinetics and biodistribution, leading to more precise drug delivery to target tissues while minimizing adverse effects.

Bioconjugation: In bioconjugation applications, Hydroxy-PEG7-t-butyl acetate acts as a crucial linker for binding biomolecules like proteins and peptides to various surfaces or molecules. This process facilitates the development of advanced biomaterials and diagnostic tools, improving biocompatibility, reducing immunogenicity, and extending the circulation time of biomolecules in the bloodstream.

Polymer Chemistry: A foundational component in the synthesis of functionalized polymers and hydrogels, Hydroxy-PEG7-t-butyl acetate enables the customization of materials for specific uses, such as tissue engineering and regenerative medicine. The presence of multiple functional groups allows for precise control over polymerization and the fine-tuning of material properties to meet diverse application requirements.

Diagnostics: In diagnostic applications, Hydroxy-PEG7-t-butyl acetate plays a pivotal role in enhancing the performance of biosensors and imaging agents. By incorporating this compound into diagnostic tools, scientists achieve heightened sensitivity and specificity in detecting biological molecules, leading to improved accuracy in medical diagnostics and early disease detection.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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