Hydrazide-PEG4-Desthiobiotin

Name: Hydrazide-PEG4-Desthiobiotin
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-2223

Purity: >95%

4.5

Hydrazide-PEG4-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker. Hydrazide-PEG4-Desthiobiotin can be used in the synthesis of a series of PROTACs.

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C₂₁H₄₁N₅O₇
Molecular Weight	475.58
Appearance	Transparent Liquid
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Structure of Hydrazide-PEG4-Desthiobiotin

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Hydrazide-PEG4-Desthiobiotin; HY-134722; CS-0148310
IUPACName	6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanehydrazide
CanonicalSMILES	CC1C(NC(=O)N1)CCCCCC(=O)NN
InChI	InChI=1S/C10H20N4O2/c1-7-8(13-10(16)12-7)5-3-2-4-6-9(15)14-11/h7-8H,2-6,11H2,1H3,(H,14,15)(H2,12,13,16)/t7-,8+/m0/s1
InChIKey	UCPUWIXGSQHNBO-JGVFFNPUSA-N
Purity	>95%

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Monofunctional (Reactive)

ReactiveToward	Terminal Alkynes; Strained Alkynes (DBCO/BCN)
ReactionChemistry	CuAAC Click Chemistry; SPAAC Click Chemistry
BiomoleculeCompatibility	Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes; Biotin/Avidin Affinity Systems
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Biotin / Desthiobiotin Affinity-Probe Construction