Fmoc-N-amido-PEG24-propionic acid

Name: Fmoc-N-amido-PEG24-propionic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 2170484-59-8

Cat No.: BPG-2663

Purity: >95%

HNMR

4.5

Fmoc-N-PEG24-acid is a polyethylene glycol (PEG)-based PROTAC linker. Fmoc-N-PEG24-acid can be used in the synthesis of a series of PROTACs.

Category	Small-molecule Group Protected PEG
Molecular Formula	C₆₆H₁₁₃NO₂₈
Molecular Weight	1368.59
Appearance	White Solid
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Structure of 2170484-59-8

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Synonyms	Fmoc-NH-PEG24-CH2CH2COOH
IUPACName	3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CanonicalSMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C66H113NO28/c68-65(69)9-11-71-13-15-73-17-19-75-21-23-77-25-27-79-29-31-81-33-35-83-37-39-85-41-43-87-45-47-89-49-51-91-53-55-93-57-58-94-56-54-92-52-50-90-48-46-88-44-42-86-40-38-84-36-34-82-32-30-80-28-26-78-24-22-76-20-18-74-16-14-72-12-10-67-66(70)95-59-64-62-7-3-1-5-60(62)61-6-2-4-8-63(61)64/h1-8,64H,9-59H2,(H,67,70)(H,68,69)
InChIKey	NFOMZHGRFWXDGH-UHFFFAOYSA-N
Purity	>95%

ReactiveToward	Primary Amines (after activation)
ReactionChemistry	Carbodiimide-Mediated Amide Coupling (EDC/NHS)
BiomoleculeCompatibility	Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation