Fmoc-N-amido-PEG1-acetic acid

Name: Fmoc-N-amido-PEG1-acetic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 260367-12-2

Cat No.: BPG-1994

Purity: ≥95%

4.5

Fmoc-N-amido-PEG1-acetic acid is a PEG-based spacer and synthetic linker building block used to introduce a defined hydrophilic and flexible segment into multistep conjugation designs. The PEG chain can increase molecular spacing and provide a modular connection between reactive groups without serving as a dedicated cleavage trigger. This derivative contains peg1 spacer together with terminal functionality selected for further synthesis. The available reactive group is no dedicated antibody-reactive group unless activated/functionalized; terminal functionality depends on the specific peg derivative. The opposite terminus provides terminal carboxylic acid; activate for coupling to an amine-bearing payload. Coupling and deprotection conditions should be matched to the terminal groups and the intended order of assembly.

Category	Fmoc-NH-PEGn-CH2COOH
Molecular Formula	C19H19NO5
Molecular Weight	341.36
Appearance	Pale Yellow or Colorless Oily Matter
Shipping	Room temperature
Storage	Store at -20°C, keep in dry and avoid sunlight

Structure of 260367-12-2

Ordering Information

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Specification
Reaction & Conjugation Properties

Synonyms	Fmoc-NH-PEG1-CH2COOH; Fmoc-O1Pen-OH; 5- (Fmoc- amino) - 3- oxapentanoic Acid; 5-(9-Fluorenylmethyloxycarbonyl-amino)-3-oxapentanoic acid; Acetic acid, 2-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-; Fmoc-AEA-OH; 2-[2-(Fmoc-amino)ethoxy]acetic Acid
IUPACName	2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]acetic acid
CanonicalSMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCC(=O)O
InChI	InChI=1S/C19H19NO5/c21-18(22)12-24-10-9-20-19(23)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17H,9-12H2,(H,20,23)(H,21,22)
InChIKey	LBVXPUINIMIGAU-UHFFFAOYSA-N
BoilingPoint	602.6±40.0°C (Predicted)
MeltingPoint	83-89°C
FlashPoint	294.8±30.1 °C
Purity	≥95%
Density	1.287±0.06 g/cm3 (Predicted)
Solubility	Soluble in DMSO (10 mm)
RelatedCAS	675606-79-8 (polymer)
Application	2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)acetic Acid can be used as reactant/reagent in modular platform to develop peptoid-based selective fluorescent metal sensors.
ExactMass	341.12632271
VaporPressure	0.0±1.6 mmHg at 25°C
LogP	3.18

Application

2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)acetic Acid can be used as reactant/reagent in modular platform to develop peptoid-based selective fluorescent metal sensors.