DSPE-PEG-COOH, MW 1k-5k
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Category | DSPE-PEG-COOH |
Catalog NO. | BPG-1222 |
Product Name | DSPE-PEG-COOH, MW 1k-5k |
Molecular Formula | C46H88NO13P |
Molecular Weight | Customizable |
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- Custom Synthesis
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Fast track to get specific molecular weight products:
Catalog | Molecular Weight | Availability | |
---|---|---|---|
BPG-1222-1 | DSPE-PEG-COOH, MW 1k | In stock | Inquiry |
BPG-1222-2 | DSPE-PEG-COOH, MW 2k | In stock | Inquiry |
BPG-1222-3 | DSPE-PEG-COOH, MW 3.4k | In stock | Inquiry |
BPG-1222-4 | DSPE-PEG-COOH, MW 5k | In stock | Inquiry |
- Product Information
- Application
- References
- Documents
- Reviews
Description | DSPE-PEG-COOH is a heterobifunctional PEG derivative. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. Phospholipids are amphiphilic. It is a preferred material for the formation of liposomes. It can be used to target drug research or cross-linking of protein carriers and ligands. It can also be used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. |
Synonyms | DSPE-PEG-CH2COOH, MW 3,400; 754180-82-0; DSPE-PEG-COOH; DTXSID701100333; G68015; 2665069-75-8 |
IUPAC Name | 2-[2-[2-[2,3-di(octadecanoyloxy)propoxy-hydroxyphosphoryl]oxyethylcarbamoyloxy]ethoxy]acetic acid |
Canonical SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCC(=O)O)OC(=O)CCCCCCCCCCCCCCCCC |
InChI | InChI=1S/C46H88NO13P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(50)57-39-42(40-59-61(53,54)58-36-35-47-46(52)56-38-37-55-41-43(48)49)60-45(51)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h42H,3-41H2,1-2H3,(H,47,52)(H,48,49)(H,53,54) |
InChIKey | MKQJGDXUKIHRCA-UHFFFAOYSA-N |
Solubility | Soluble in water, DMSO and DMF. Freshly prepared before use. |
Storage | -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing. |
References | 1. Zhao, Bo-Jun, et al. The antiangiogenic efficacy of NGR-modified PEG-DSPE micelles containing paclitaxel (NGR-M-PTX) for the treatment of glioma in rats.Journal of drug targeting, 2011, 19(5): 382-390. 2. Maruyama, Kazuo. PEG-immunoliposome.Bioscience reports, 2002, 22(2): 251-266. |
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Resources
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Technical Information
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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