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DMHAPC-Chol

CAS No. CAS No.: 794494-38-5
Cat No. Cat No.: BPG-3624
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DMHAPC-Chol is a cationic cholesterol. In tests using a B16-F10 mouse xenograft model, liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo. Liposomes containing concentrations greater than 20 μM DMHAPC-chol have been found to be cytotoxic to B16-F10 cells when used at lipid.

Category Cholesterol
Molecular Formula C35H63N2O3
Molecular Weight 559.9
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Storage -20°C
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DMHAPC-Chol

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  • Specification
Synonyms DMHAPC-Chol; 794494-38-5; 3-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxycarbonylamino]propyl-(2-hydroxyethyl)-dimethylazanium; (3beta)-cholest-5-en-3-ol 3-[N-[3-[(2-hydroxyethyl)dimethylammonio]propyl]carbamate]; AKOS040755919; BP-29629; DMHAPC-Chol, Dimethyl Hydroxyethyl Aminopropane Carbamoyl Cholesterol Iodide
IUPACName 3-[[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxycarbonylamino]propyl-(2-hydroxyethyl)-dimethylazanium
CanonicalSMILES CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)NCCC[N+](C)(C)CCO)C)C
InChI InChI=1S/C35H62N2O3/c1-25(2)10-8-11-26(3)30-14-15-31-29-13-12-27-24-28(16-18-34(27,4)32(29)17-19-35(30,31)5)40-33(39)36-20-9-21-37(6,7)22-23-38/h12,25-26,28-32,38H,8-11,13-24H2,1-7H3/p+1/t26-,28+,29+,30-,31+,32+,34+,35-/m1/s1
InChIKey ZTGXTDBNSSOEDB-SJTWHRLHSA-O

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