DBCO-NH-PEG4-maleimide

Name: DBCO-NH-PEG4-maleimide
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 1480516-75-3

Cat No.: BPG-2467

Purity: >98.0%

4.5

DBCO-NH-PEG4-maleimide is a heterobifunctional ADC linker combining maleimide thiol-reactivity and DBCO for SPAAC click chemistry, facilitating versatile and stable antibody-drug conjugate formation.

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C36H42N4O9
Molecular Weight	674.74
Appearance	Solid
Shipping	-20°C (International: -20°C)
Storage	Store at -20 °C, keep in dry and avoid sunlight.

Structure of 1480516-75-3

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

Fast-Track Access to Precise Molecular Weight Products

Professional Solutions for Molecular Research

cGMP Capacity

cGMP-compliant manufacturing options
Comprehensive QC testing with COA, MSD
From mg and g to kg-scale production
In-stock supply in the US and Europe
Global supply & fast worldwide delivery
One-stop PEGylation services
Custom PEG reagents synthesis
Click chemistry reagents
Bioconjugation & drug delivery
Trusted by 100+ research institutions

Popular Publications Citing BOC Sciences Products

Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	DBCO-PEG4-Maleimide;DBCO-NH-PEG4-Maleimide; DBCO-PEG4-MAL
IUPACName	N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
CanonicalSMILES	C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN4C(=O)C=CC4=O
InChI	InChI=1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)
InChIKey	VVFZXPZWVJMYPX-UHFFFAOYSA-N
BoilingPoint	965.2±65.0 °C at 760 mmHg
FlashPoint	537.6±34.3 °C
Purity	>98.0%
Density	1.3±0.1 g/cm3
Solubility	10 mm in DMSO
ShelfLife	-20°C 3 years powder; -80°C 2 years in solvent
VaporPressure	0.0±0.3 mmHg at 25°C
LogP	1.22

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Azides; Thiols
ReactionChemistry	SPAAC Click Chemistry; Maleimide-Thiol Conjugation
BiomoleculeCompatibility	Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes; Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Thiol-Selective Biomolecule Conjugation