cRGD-PEG-NHS, MW 1k

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	cRGD-PEG-NHS
Catalog NO.	BPG-1552
Product Name	cRGD-PEG-NHS, MW 1k

Scheme Design
Custom Synthesis
cGMP Manufacturing
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Product Information
Application
References
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Reviews

Product Information

Description	Arg-Gly-Asp (RGD) polypeptide is a common tumor active targeting polypeptide that can directly act on tumor targets to form an active targeting effect. The applications of RGD peptides includes inhibition of apoptosis, angiogenesis and tumor formation. RGD peptides are used as coating surfaces for biomaterials to enhance drug delivery and imaging for disease diagnosis. PEGylated RGD can be cross-linked with other molecules via reactive terminal groups on PEG for use in various biomedical studies.
Solubility	Soluble in water, DMSO and DMF. Freshly prepared before use.
Storage	-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.

References

1. Li L, Yang J, Wang W W, et al. Pigment epithelium-derived factor gene loaded in cRGD-PEG-PEI suppresses colorectal cancer growth by targeting endothelial cells. International journal of pharmaceutics, 2012, 438(1-2): 1-10.
2. Zhu Y, Zhang J, Meng F, et al. cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo. Journal of Controlled Release, 2016, 233: 29-38.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.