| Category | Cholesterol |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.66 |
| Appearance | White or almost white powder |
| Storage | Store at -20 °C |
Cholesterol
Cholesterol is a sterol lipid and an essential structural component of mammalian cell membranes, maintaining membrane fluidity and integrity. It serves as a precursor for steroid hormones, bile acids, and vitamin D synthesis. In pharmaceutical formulations, cholesterol is widely used as an excipient in liposomes and lipid nanoparticles (LNPs), where it enhances membrane stability, reduces permeability, and improves drug encapsulation efficiency. It also acts as an emulsifier and stabilizer in various drug delivery systems.
Structure of 57-88-5
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| Synonyms | Cholest-5-en-3β-ol; (3β)-Cholest-5-en-3-ol; Cholesterin; cholesterolum; Cholesteryl alcohol; Cholestrin; Cordulan; Dusoline; Dythol; Kathro; Lanol; Super hartolan |
| IUPACName | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| CanonicalSMILES | CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C |
| InChI | InChI=1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 |
| InChIKey | HVYWMOMLDIMFJA-DPAQBDIFSA-N |
| BoilingPoint | 480.6±14.0 °C at 760 mmHg |
| MeltingPoint | 148-150 °C |
| FlashPoint | 250 °C |
| Purity | >98% |
| Density | 1.06 g/cm3 |
| Solubility | Soluble in Acetone, Benzene, Chloroform, Ethanol, Ether, Methanol |
| ExactMass | 386.355 |
| Hygroscopic | No |
| LightSensitive | No |
| PercentComposition | C 83.87%, H 11.99%, O 4.14% |
| VaporPressure | VP: 0.171 mm Hg at 149 °C |
| Decomposition | When heated to decomposition it emit acrid smoke and irritating fumes. |
| RefractiveIndex | 1.525 |
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