C18-PEG4-NH2, PEG MW 176 Da

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Category	C18-PEG-NH2
Catalog NO.	BPG-0389
Product Name	C18-PEG4-NH2, PEG MW 176 Da

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Product Information

Description	The PEG derivatives of the C18-PEG(n) series also belong to monodisperse PEG. It is a linear PEG derivative with 18 linear carbon straight chains and a different reactive group at the other end that can modify peptides, proteins, lipids or small molecules. The amine is reactive with carboxylic acid in the presence of DCC/EDC and NHS. As a drug crosslinker, it is widely used in medical research. Drug PEG modification can alter its dispersion and solubility in aqueous solutions. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system.
Synonyms	Tetraethylene glycol octadecyl ether amine
Solubility	Soluble in water, DMSO and DMF. Freshly prepared before use.
Storage	-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.

References

1. Huang L, Song J, Chen B. A novel targeting drug carrier to deliver chemical bonded and physical entrapped anti-tumor drugs. International journal of pharmaceutics, 2014, 466(1-2): 52-57.
2. Zhu S, Niu M, O'Mary H, et al. Targeting of tumor-associated macrophages made possible by PEG-sheddable, mannose-modified nanoparticles. Molecular pharmaceutics, 2013, 10(9): 3525-3530.

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