| Category | Small-molecule Biotin PEG |
| Molecular Formula | C22H34N4O7S |
| Molecular Weight | 498.60 |
| Storage | Store at -20 °C |
Biotinyl-PEG3-Mal
Biotinyl-PEG3-Mal is a functionalized PEG linker featuring a biotin moiety attached to a three-unit PEG spacer and terminated with a maleimide group. This compound is used in bioconjugation reactions, particularly for labeling and functionalizing biomolecules. The maleimide group allows for the conjugation to thiol groups, enabling the attachment of biotin to proteins or other biomolecules.
Structure of Biotinyl-PEG3-Mal
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | Biotin-PEG3-Maleimide; Maleimide-PEG3-Biotin; 5-[(3aS,4S,6aR)-2-Oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(2-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}ethoxy)ethyl]pentanamide; Biotin-PEG(3)-Mal; Biotin-TEG-Mal; Biotinyl-PEG(3)-Mal; Biotin-PEG(3)-Maleimide; Maleimide-PEG(3)-Biotin; Mal-PEG(3)-Biotin; Mal-TEG-Biotin; Biotin-PEG3-Mal |
| IUPACName | N-(2-(2-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
| CanonicalSMILES | O=C(NCCOCCOCCOCCN1C(C=CC1=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O |
| InChI | InChI=1S/C22H34N4O7S/c27-18(4-2-1-3-17-21-16(15-34-17)24-22(30)25-21)23-7-9-31-11-13-33-14-12-32-10-8-26-19(28)5-6-20(26)29/h5-6,16-17,21H,1-4,7-15H2,(H,23,27)(H2,24,25,30)/t16-,17-,21-/m0/s1 |
| InChIKey | ISALCRNLMVRBLT-FIKGOQFSSA-N |
| Purity | >98% |
| PEGType | Discrete PEG Linker |
| PEGArchitecture | Linear |
| Functionality | Monofunctional (Reactive) |
| ReactiveToward | Thiols |
| ReactionChemistry | Maleimide-Thiol Conjugation |
| BiomoleculeCompatibility | Biotin/Avidin Affinity Systems; Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides |
| ResearchUse | Thiol-Selective Biomolecule Conjugation; Biotin / Desthiobiotin Affinity-Probe Construction |
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