Biotin-PEG4-hydrazide
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| Category | Biotin PEG |
| Catalog NO. | BPG-2273 |
| Product Name | Biotin-PEG4-hydrazide |
| CAS | 756525-97-0 |
| Molecular Formula | C₂₁H₃₉N₅O₇S |
| Molecular Weight | 505.63 |
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| Description | Biotin-PEG4-hydrazide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG4-hydrazide can be used in the synthesis of a series of PROTACs. |
| Synonyms | (+)-Biotin-PEG4-Hydrazide; (+)-Biotin-PEG4-NHNH2; Biotin-PEG4-NHNH2 |
| IUPAC Name | N-[2-[2-[2-[2-(3-hydrazinyl-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethyl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide |
| Canonical SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)NN)NC(=O)N2 |
| InChI | InChI=1S/C21H39N5O7S/c22-26-19(28)5-7-30-9-11-32-13-14-33-12-10-31-8-6-23-18(27)4-2-1-3-17-20-16(15-34-17)24-21(29)25-20/h16-17,20H,1-15,22H2,(H,23,27)(H,26,28)(H2,24,25,29) |
| InChIKey | PSBJJOWIACLJAQ-UHFFFAOYSA-N |
| Boiling Point | 825.5±65.0 °C at 760 mmHg |
| Purity | >95% |
| Density | 1.2±0.1 g/cm3 |
| Appearance | White Solid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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Industry News
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- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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