Azido-PEG8-propionic acid
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Small-molecule Heterobifunctional PEG |
Catalog NO. | BPG-2210 |
Product Name | Azido-PEG8-propionic acid |
CAS | 1214319-92-2 |
Molecular Formula | C19H37N3O10 |
Molecular Weight | 467.51 |
- Scheme Design
- Custom Synthesis
- cGMP Manufacturing
- Quality Assurance
- Product Information
- Application
- References
- Documents
- Reviews
Description | Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Synonyms | Azido-PEG8-acid;N3-PEG8-COOH; Azido-PEG8-C2-acid; Azido-PEG8-Acid; N3-PEG8-CH2CH2COOH; 1-Azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid; 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-azido-; Azido-dPEG(R)8-acid |
IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)O |
InChI | InChI=1S/C19H37N3O10/c20-22-21-2-4-26-6-8-28-10-12-30-14-16-32-18-17-31-15-13-29-11-9-27-7-5-25-3-1-19(23)24/h1-18H2,(H,23,24) |
InChIKey | URUGOEBULOZLBF-UHFFFAOYSA-N |
Purity | ≥95% |
Solubility | Soluble in DCM, DMF, DMSO, Water |
Related CAS | 1167575-20-3 (polymer) |
Appearance | Pale Yellow Oily Matter |
Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
Storage | Store at 2-8°C |
Azido-PEG8-propionic acid, a versatile chemical reagent, plays a pivotal role in bioconjugation and biomedical research. Here are four key applications of Azido-PEG8-propionic acid presented with high perplexity and burstiness: Bioconjugation: A cornerstone of bioconjugation, Azido-PEG8-propionic acid serves as a linchpin in linking biomolecules like proteins, peptides, and antibodies to diverse surfaces or tags. Its azide group engages in precise click chemistry reactions with alkynes, fostering the formation of sturdy covalent bonds. This process facilitates the functionalization of biomolecules, propelling advancements in diagnostics, drug delivery, and biosensor development. Drug Delivery Systems: Delving into the realm of drug delivery systems, Azido-PEG8-propionic acid emerges as a game-changer, enhancing the delivery and therapeutic efficacy of drug molecules or carriers. The PEG moiety imparts heightened solubility and diminished immunogenicity, while the azido group enables site-specific conjugation. This refined approach augments the precision in targeting and releasing drugs at designated sites within the body, revolutionizing treatment outcomes. Surface Functionalization: In the intricate field of materials science, Azido-PEG8-propionic acid finds application in the functionalization of surfaces like nanoparticles, hydrogels, and medical devices. This compound is instrumental in attaching bioactive molecules or probes to surfaces via click chemistry, crafting biofunctional interfaces. Such innovations prove invaluable in the development of biosensors, tissue engineering scaffolds, and biocompatible coatings, driving progress in diverse sectors. Protein Labeling: Azido-PEG8-propionic acid emerges as a key player in protein labeling within proteomics and cell biology landscapes. By integrating this reagent into proteins, researchers can affix fluorescent dyes or other tags, facilitating visualization and tracking of proteins amidst complex biological systems. This application holds profound significance in unraveling protein localization, interactions, and dynamics, offering invaluable insights into cellular processes. |
Reviews
If you have any suggestions or comments about mPEG-Br, please submit a review immediately.
Why BOC Sciences?
-
Large Stock
More than 2000+ products in inventory
-
Global Delivery
Warehouses in multiple cities to ensure fast delivery
-
mg to kg
Multi specification for academic research and industrial production
-
24/7 Technical Support
Strict process parameter control to ensure product quality
Products
- Lipids
- PEG Derivatives by Structure
-
PEG Derivatives by Functional Group
- Acrylate/Acrylamide/Methacrylate PEG
- Aldehyde (Ald/CHO)PEG
- Alkyne PEG
- Amino PEG, PEG amine(-NH2)
- Azide PEG, Azido PEG(-N3)
- Biotin PEG
- Boc/Fmoc protected amine PEG
- Carboxylic Acid(-COOH) PEG
- Cholesterol PEG
- DBCO PEG
- DNP PEG
- DSPE PEG
- Epoxide glycidyl ether PEG
- FITC PEG
- Folate PEG
- Halide (chloride, bromide) PEG
- Hydrazide PEG
- Hydroxyl(-OH) PEG
- Maleimide(-MAL) PEG
- NHS ester PEG
- Nitrophenyl carbonate (NPC) PEG
- Norbornene PEG
- Olefin/Alkene/Vinyl PEG
- Orthopyridyl disulfide (OPSS) PEG
- Phosphate PEG
- Rhodamine PEG
- SCM PEG
- Silane PEG
- SPDP PEG
- Sulfonate (tosyl, mesyl, tresyl) PEG
- tert-Butyl protected carboxylate PEG
- Thiol(-SH) PEG
- Vinylsulfone PEG
- PEG Copolymers
-
PEG Raw Materials
- Small-molecule Polyethylene Glycol
- Polyethylene Glycol 1000
- Polyethylene Glycol 10000
- Polyethylene Glycol 1500
- Polyethylene Glycol 200
- Polyethylene Glycol 2000
- Polyethylene Glycol 20000
- Polyethylene Glycol 400
- Polyethylene Glycol 4000
- Polyethylene Glycol 600
- Polyethylene Glycol 6000
- Polyethylene Glycol 800
- Polyethylene Glycol 8000
Resources
-
Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
-
Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
Learn More
APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
Learn More
Have Customer Reviewed On Us?
Chat With Us