| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C27H53N3O14 |
| Molecular Weight | 643.72 |
| Appearance | White Solid |
| Storage | Store at 4°C |
Azido-PEG12-propionic acid
Azido-PEG12-propionic acid is a heterobifunctional PEG linker containing an azide group and a carboxylic acid. The azide group reacts with terminal alkynes and cyclooctyne derivatives via click chemistry, and the carboxylic acid can be reacted with amino groups in the presence of activators.
Structure of 1167575-20-3
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- Specification
- Reaction & Conjugation Properties
| Synonyms | N3-PEG12-COOH;Azido-PEG36-acid;N3-PEG12-CH2CH2COOH |
| IUPACName | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)O |
| InChI | InChI=1S/C27H53N3O14/c28-30-29-2-4-34-6-8-36-10-12-38-14-16-40-18-20-42-22-24-44-26-25-43-23-21-41-19-17-39-15-13-37-11-9-35-7-5-33-3-1-27(31)32/h1-26H2,(H,31,32) |
| InChIKey | DYFODOGACDHUBQ-UHFFFAOYSA-N |
| Purity | >97% |
| Solubility | Water, DMSO, DCM, DMF |
| Application | Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Monodisperse Azido-PEG12-acid (N3-PEG12-COOH) is a heterobifunctional PEG linker containing an azide (N3) group and a carboxylic acid (COOH). The azide group reacts with terminal alkynes and cyclooctyne derivatives via click chemistry, and the carboxylic acid can be reacted with amino groups in the presence of activators. |
| Application | Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Monodisperse Azido-PEG12-acid (N3-PEG12-COOH) is a heterobifunctional PEG linker containing an azide (N3) group and a carboxylic acid (COOH). The azide group reacts with terminal alkynes and cyclooctyne derivatives via click chemistry, and the carboxylic acid can be reacted with amino groups in the presence of activators. |
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