Azido-PEG8-CH2CH2COOTFP ester

Name: Azido-PEG8-CH2CH2COOTFP ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-2412

Purity: >95%

4.5

Azido-PEG8-CH2CH2COOTFP ester is a heterobifunctional PEG linker containing an azide group and a TFP group. The azide group reacts with terminal alkynes and cyclooctyne derivatives via click chemistry, and the TFP group is amine-reactive that is used to attach fluorophores or haptens to the primary amines of biomolecules.

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C25H37F4N3O10
Molecular Weight	615.57
Appearance	Transparent Liquid
Storage	Store at -20°C

Structure of Azido-PEG8-CH2CH2COOTFP ester

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Azido-PEG8-TFP ester
CanonicalSMILES	C1=C(C(=C(C(=C1F)F)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])F)F
InChI	InChI=1S/C25H37F4N3O10/c26-20-19-21(27)24(29)25(23(20)28)42-22(33)1-3-34-5-7-36-9-11-38-13-15-40-17-18-41-16-14-39-12-10-37-8-6-35-4-2-31-32-30/h19H,1-18H2
InChIKey	ICPUCGMOWKDMAI-UHFFFAOYSA-N
Purity	>95%

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Monofunctional (Reactive)

ReactiveToward	Terminal Alkynes; Strained Alkynes (DBCO/BCN); Primary Amines
ReactionChemistry	CuAAC Click Chemistry; SPAAC Click Chemistry; Activated-Ester Amine Coupling
BiomoleculeCompatibility	Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Amine-Selective Biomolecule Coupling