Azido-PEG4-t-butyl acetate

Name: Azido-PEG4-t-butyl acetate
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 864681-04-9

Cat No.: BPG-1976

Purity: >98.0%

4.5

Azido-PEG4-t-butyl acetate is a PEG-containing bioorthogonal conjugation building block that provides an azide handle for modular click-chemistry workflows. The molecule can be used to introduce a click-reactive group onto an antibody, peptide, linker intermediate, or payload-containing component, depending on the chemistry of its second terminal functionality. Its additional reactive group is azide bioorthogonal handle; requires complementary click handle on the antibody. The structure includes peg4 spacer to provide hydrophilic spacing. Conjugation can be performed using spaac with dbco/bcn-functionalized partner or cuaac with terminal alkyne partner, depending the complementary handle. The sequence and orientation of the coupling steps should be selected according to the functional groups carried by the two conjugation partners.

Category	Small-molecule Group Protected PEG
Molecular Formula	C14H27N3O6
Molecular Weight	333.38
Appearance	Solid
Shipping	Room temperature, or blue ice upon request.
Storage	-20°C

Structure of 864681-04-9

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

Fast-Track Access to Precise Molecular Weight Products

Professional Solutions for Molecular Research

cGMP Capacity

cGMP-compliant manufacturing options
Comprehensive QC testing with COA, MSD
From mg and g to kg-scale production
In-stock supply in the US and Europe
Global supply & fast worldwide delivery
One-stop PEGylation services
Custom PEG reagents synthesis
Click chemistry reagents
Bioconjugation & drug delivery
Trusted by 100+ research institutions

Popular Publications Citing BOC Sciences Products

Specification

Synonyms	Tert-butyl 14-azido-3,6,9,12-tetraoxatetradecanoate; Azido-PEG4-CH2CO2-t-Bu
IUPACName	tert-butyl 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetate
CanonicalSMILES	CC(C)(C)OC(=O)COCCOCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C14H27N3O6/c1-14(2,3)23-13(18)12-22-11-10-21-9-8-20-7-6-19-5-4-16-17-15/h4-12H2,1-3H3
InChIKey	SIOLYQZSIFQODW-UHFFFAOYSA-N
Purity	>98.0%
Solubility	10 mm in DMSO
ShelfLife	0-4°C for short term (days to weeks), or -20°C for long term (months).
LogP	1.15756