Azido-PEG11-alcohol

Azido-PEG11-alcohol is a versatile linker molecule used extensively in biochemical and medical applications. Here are some key applications of Azido-PEG11-alcohol:

Bioconjugation: Azido-PEG11-alcohol can be used to couple biological molecules such as peptides, proteins, and antibodies to various surfaces or other biomolecules via click chemistry. This enables the creation of multifunctional complexes for applications in diagnostics, therapeutics, and biosensing. The PEG spacer improves solubility and biocompatibility, enhancing the performance of the conjugates.

Drug Delivery Systems: In drug delivery research, Azido-PEG11-alcohol is employed to modify and functionalize nanoparticles, liposomes, and other carriers. This modification allows for the targeted delivery of therapeutic agents to specific cells or tissues while minimizing off-target effects. The azido group facilitates site-specific functionalization, improving the pharmacokinetics and biodistribution of drug delivery systems.

Surface Modification: Azido-PEG11-alcohol is used to functionalize surfaces like glass, gold, and polymers, which is essential in fabricating biosensors and diagnostic devices. The introduction of azido groups provides reactive sites for subsequent attachment of biomolecules through click chemistry. This results in the generation of stable and highly specific biointerfaces for detecting and studying biological interactions.

Protein Engineering: Azido-PEG11-alcohol can be used to introduce azido groups into proteins through site-specific modification, facilitating further functionalization. This allows for the creation of custom-engineered proteins with tailored properties for research and therapeutic uses. The PEGylation aspect helps in improving protein solubility, stability, and reducing immunogenicity, which is critical for biopharmaceutical applications.