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Amino-PEG12-propionic acid
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2414 |
| Product Name | Amino-PEG12-propionic acid |
| CAS | 1415408-69-3 |
| Molecular Formula | C₂₇H₅₅NO₁₄ |
| Molecular Weight | 617.72 |
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| Description | Amino-PEG12-acid is a polyethylene glycol (PEG)-based PROTAC linker. Amino-PEG12-acid can be used in the synthesis of a series of PROTACs. |
| Synonyms | Amino-PEG12-COOH; Amino-PEG12-acid; α-amine-ω-propionic acid dodecaethylene glycol |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)C(=O)O |
| InChI | InChI=1S/C27H55NO14/c28-2-4-32-6-8-34-10-12-36-14-16-38-18-20-40-22-24-42-26-25-41-23-21-39-19-17-37-15-13-35-11-9-33-7-5-31-3-1-27(29)30/h1-26,28H2,(H,29,30) |
| InChIKey | NLXRBQLQDLAFIM-UHFFFAOYSA-N |
| Boiling Point | 665.8±55.0 °C at 760 mmHg |
| Purity | >97% |
| Density | 1.1±0.1 g/cm3 |
| Related CAS | 1818294-41-5 (polymer) 196936-04-6 (polymer) |
| Appearance | White Powder |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
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- Introduction of Polyethylene Glycol (PEG)
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
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- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
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- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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PEGylation of Peptides
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