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3,6,9,12,15,18,21,24-Octaoxahexacosanedioic acid

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Category COOH-CH2-PEGn-CH2-COOH
Catalog NO. BPG-1541
Product Name 3,6,9,12,15,18,21,24-Octaoxahexacosanedioic acid
CAS 910138-50-0
Molecular Formula C18H34O12
Molecular Weight 442.46
3,6,9,12,15,18,21,24-Octaoxahexacosanedioic acid
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Product Information

Description 3,6,9,12,15,18,21,24-Octaoxahexacosanedioic acid is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.
Synonyms COOH-CH2-PEG8-CH2-COOH; COOH-CH2-PEG7-CH2-COOH; HOOCCH2O-PEG7-CH2COOH; Octaoxahexacosanedioic Acid Bis(N-Hydroxysuccinimide) Ester; 3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-dioic acid
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES C(COCCOCCOCCOCC(=O)O)OCCOCCOCCOCC(=O)O
InChI InChI=1S/C18H34O12/c19-17(20)15-29-13-11-27-9-7-25-5-3-23-1-2-24-4-6-26-8-10-28-12-14-30-16-18(21)22/h1-16H2,(H,19,20)(H,21,22)
InChIKey WEXXDWCCIJEREI-UHFFFAOYSA-N
Boiling Point 583.0±45.0°C at 760 mmHg
Purity ≥95%
Density 1.2±0.1 g/cm3
Storage Store at 2-8°C
Exact Mass 442.20502652
References Norgard, K., et al. J. Biol. Chem., 268, 12764 (1993), Lin, C., et al. Bioorg. Med. Chem., 3, 1625 (1995), Steegmaier, M., et al. Nature, 373, 615 (1995), Murray, B., et al. Biochemistry, 35, 11183 (1996),.

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