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16:1 (n7) Coenzyme A ammonium salt

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Category Acyl CoA - Saturated Fatty Acid
Catalog NO. BPG-3065
Product Name 16:1 (n7) Coenzyme A ammonium salt
CAS 1246304-41-5
Molecular Formula C37H73N10O17P3S
Molecular Weight 1055.02
16:1 (n7) Coenzyme A ammonium salt
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Description 16:1 (n7) Coenzyme A ammonium salt, a vital catalyst in fatty acid metabolism, contributes significantly to the therapeutic management of lipid metabolism dysfunctions and fatty acid oxidation anomalies. Moreover, its utility extends to pharmaceutical advancements aimed at combating metabolic conditions like obesity and diabetes.
Synonyms palmitoleoyl Coenzyme A (ammonium salt); (9Z-hexadecenoyl) Coenzyme A (ammonium salt)
IUPAC Name S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-hexadec-9-enethioate;azane
Canonical SMILES CCCCCCC=CCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O.N.N.N
InChI InChI=1S/C37H64N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44;;;/h9-10,24-26,30-32,36,47-48H,4-8,11-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52);3*1H3/b10-9-;;;/t26-,30-,31-,32+,36-;;;/m1.../s1
InChIKey BZLFGTFLKXOWRJ-SZUAKDMZSA-N
Purity >99%
Appearance Powder
Shelf Life 1 Year
Storage Store at -20°C
Exact Mass 1054.409
Hygroscopic No
Light Sensitive No
Percent Composition C 42.12%, H 6.97%, N 13.28%, O 25.78%, P 8.81%, S 3.04%
References 1. Nam JW, Jenkins LM, Li J, Evans B, Jaworski JG, Allen DK. A General Method for Quantification and Discovery of Acyl Groups Attached to Acyl Carrier Proteins in Fatty Acid Metabolism using LC-MS/MS. Plant Cell. 2020 Feb 14:tpc.00954.2019. doi: 10.1105/tpc.19.00954. Epub ahead of print. PMID: 32060179. PubMed ID: 32060179.
2. Sampath H, Ntambi JM. Role of stearoyl-CoA desaturase-1 in skin integrity and whole body energy balance. J Biol Chem. 2014 Jan 31;289(5):2482-8. doi: 10.1074/jbc.R113.516716. Epub 2013 Dec 19. PMID: 24356954; PMCID: PMC3908384. PubMed ID: 24356954.

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