| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C10H22N4O3 |
| Molecular Weight | 246.30 |
| Appearance | Light yellow oil |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Store at 2-8 °C |
1-Azido-4,7,10-trioxa-13-tridecanamine
1-Azido-4,7,10-trioxa-13-tridecanamine is an azido-functionalized, polyether-based compound frequently utilized in bioorthogonal chemistry. Its terminal azide group participates efficiently in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating site-specific conjugation and labeling of biomolecules. The flexible, hydrophilic backbone, derived from repeating ethylene glycol units, enhances solubility and molecular accessibility. Researchers employ this reagent extensively in peptide engineering, therapeutic delivery systems, and protein modification strategies.
Structure of 1162336-72-2
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- Specification
| Synonyms | 1-Amino-11-azido-3,6,9-trioxaundecane; N3-TOTA; 3-[2-[2-(3-Azidopropoxy)ethoxy]ethoxy]propan-1-amine |
| IUPACName | 3-[2-[2-(3-azidopropoxy)ethoxy]ethoxy]propan-1-amine |
| CanonicalSMILES | C(CN)COCCOCCOCCCN=[N+]=[N-] |
| InChI | InChI=1S/C10H22N4O3/c11-3-1-5-15-7-9-17-10-8-16-6-2-4-13-14-12/h1-11H2 |
| InChIKey | VJXPLUVBIHOQFJ-UHFFFAOYSA-N |
| BoilingPoint | 198-202°C |
| Purity | ≥ 98% (TLC) |
| Density | 1.10 g/mL at 20 °C(lit.) |
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