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1-Azido-4,7,10-trioxa-13-tridecanamine

CAS No. CAS No.: 1162336-72-2
Cat No. Cat No.: BPG-1823
Purity Purity: ≥ 98% (TLC)
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1-Azido-4,7,10-trioxa-13-tridecanamine is an azido-functionalized, polyether-based compound frequently utilized in bioorthogonal chemistry. Its terminal azide group participates efficiently in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating site-specific conjugation and labeling of biomolecules. The flexible, hydrophilic backbone, derived from repeating ethylene glycol units, enhances solubility and molecular accessibility. Researchers employ this reagent extensively in peptide engineering, therapeutic delivery systems, and protein modification strategies.

Category Small-molecule Heterobifunctional PEG
Molecular Formula C10H22N4O3
Molecular Weight 246.30
Appearance Light yellow oil
Shipping Room temperature in continental US; may vary elsewhere.
Storage Store at 2-8 °C
1-Azido-4,7,10-trioxa-13-tridecanamine

Structure of 1162336-72-2

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  • Specification
Synonyms 1-Amino-11-azido-3,6,9-trioxaundecane; N3-TOTA; 3-[2-[2-(3-Azidopropoxy)ethoxy]ethoxy]propan-1-amine
IUPACName 3-[2-[2-(3-azidopropoxy)ethoxy]ethoxy]propan-1-amine
CanonicalSMILES C(CN)COCCOCCOCCCN=[N+]=[N-]
InChI InChI=1S/C10H22N4O3/c11-3-1-5-15-7-9-17-10-8-16-6-2-4-13-14-12/h1-11H2
InChIKey VJXPLUVBIHOQFJ-UHFFFAOYSA-N
BoilingPoint 198-202°C
Purity ≥ 98% (TLC)
Density 1.10 g/mL at 20 °C(lit.)

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