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Tos-PEG9-acid
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| Category | Tos-PEGn-acid |
| Catalog NO. | BPG-3447 |
| Product Name | Tos-PEG9-acid |
| CAS | 2071652-08-7 |
| Molecular Formula | C26H44O13S |
| Molecular Weight | 596.66 |
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| Description | Tos-PEG9-acid contains a tosyl group and a terminal carboxylic acid. Tosyl group is a very good leaving group for nucleophilic substitution reaction. Terminal carboxylic acid is easy to react with primary and secondary amines and form stable amide bonds in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases the solubility in aqueous media. |
| Synonyms | Tos-PEG9-COOH; 1-(tosyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | CC1=CC=C(S(=O)(OCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C=C1 |
| InChI | InChI=1S/C26H44O13S/c1-24-2-4-25(5-3-24)40(29,30)39-23-22-38-21-20-37-19-18-36-17-16-35-15-14-34-13-12-33-11-10-32-9-8-31-7-6-26(27)28/h2-5H,6-23H2,1H3,(H,27,28) |
| InChIKey | CUMISWXQXONPMQ-UHFFFAOYSA-N |
| Boiling Point | 685.6±55.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.2±0.1 g/cm3 |
| Storage | Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) |
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Industry News
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- The PROTAC Technology in Drug Development
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