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THP-PEG8-alcohol
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2190 |
| Product Name | THP-PEG8-alcohol |
| CAS | 658858-65-2 |
| Molecular Formula | C21H42O10 |
| Molecular Weight | 454.55 |
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| Description | THP-PEG8-alcohol is a THP PEG linker that may be used in the development of antibody-drug conjugates (ADCs). |
| Synonyms | OH-PEG8-THP; THP-PEG9; THP-PEG8-OH; HO-PEG8-THP; 23-(Tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol; 3,6,9,12,15,18,21-Heptaoxatricosan-1-ol, 23-[(tetrahydro-2H-pyran-2-yl)oxy]- |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Canonical SMILES | C1CCOC(C1)OCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C21H42O10/c22-4-6-23-7-8-24-9-10-25-11-12-26-13-14-27-15-16-28-17-18-29-19-20-31-21-3-1-2-5-30-21/h21-22H,1-20H2 |
| InChIKey | BMBLURHCJAQZLN-UHFFFAOYSA-N |
| Boiling Point | 537.2±50.0°C at 760 mmHg |
| Purity | >95% |
| Density | 1.1±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Related CAS | 92417-25-9 (polymer) 301295-36-3 (polymer) |
| Appearance | White Solid |
| Storage | Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) |
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Technical Information
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Industry News
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
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- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
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