Propargyl-PEG5-amine
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1869 |
| Product Name | Propargyl-PEG5-amine |
| CAS | 1589522-46-2 |
| Molecular Formula | C13H25NO5 |
| Molecular Weight | 275.34 |
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| Description | Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| Synonyms | Propargyl-PEG5-NH2 |
| IUPAC Name | 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanamine |
| Canonical SMILES | C#CCOCCOCCOCCOCCOCCN |
| InChI | InChI=1S/C13H25NO5/c1-2-4-15-6-8-17-10-12-19-13-11-18-9-7-16-5-3-14/h1H,3-14H2 |
| InChIKey | BLBTXXAWMPTQOK-UHFFFAOYSA-N |
| Boiling Point | 360.4±37.0 °C at 760 mmHg |
| Flash Point | 166.5±20.2 °C |
| Purity | >98.0% |
| Density | 1.0±0.1 g/cm3 |
| Solubility | 10 mm in DMSO |
| Appearance | Colorless Liquid |
| Shelf Life | 0-4℃ for short term (days to weeks), or -20℃ for long term (months). |
| Storage | Store at -5°C,keep in dry and avoid sunlight. |
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Industry News
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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Improved Circulation Half-Life
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