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Propargyl-PEG4-t-butyl ester
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| Category | Small-molecule Group Protected PEG |
| Catalog NO. | BPG-1947 |
| Product Name | Propargyl-PEG4-t-butyl ester |
| CAS | 1355197-66-8 |
| Molecular Formula | C16H28O6 |
| Molecular Weight | 316.39 |
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| Description | Propargyl-PEG4-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Propargyl-PEG4-Boc can be used in the synthesis of a series of PROTACs. |
| Synonyms | Propargyl-PEG4-COOtBu; Propargyl-PEG4-Boc; Alkyne-PEG4-CH2CH2COOtBu; tert-Butyl 4,7,10,13-tetraoxahexadec-15-yn-1-oate; Propargyl-PEG4-t-Bu Ester; 4,7,10,13-Tetraoxahexadec-15-ynoic acid, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl 4,7,10,13-tetraoxahexadec-15-yn-1-oate; tert-butyl 4,7,10,13-tetraoxahexadec-15-ynoate |
| IUPAC Name | tert-butyl 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoate |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCC#C |
| InChI | InChI=1S/C16H28O6/c1-5-7-18-9-11-20-13-14-21-12-10-19-8-6-15(17)22-16(2,3)4/h1H,6-14H2,2-4H3 |
| InChIKey | BEQLPTKRFULADF-UHFFFAOYSA-N |
| Boiling Point | 380.3±32.0°C at 760 mmHg |
| Purity | >95% |
| Density | 1.0±0.1 g/cm3 |
| Solubility | Soluble in DCM, DMF, DMSO |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
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