m-PEG10-COOH
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Category | Small-molecule Methoxy Linear PEG (mPEG) |
Catalog NO. | BPG-2262 |
Product Name | m-PEG10-COOH |
CAS | 2409969-94-2 |
Molecular Formula | C22H44O12 |
Molecular Weight | 500.58 |
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Description | m-PEG10-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Synonyms | m-PEG10-acid; mPEG9-propionic acid; mPEG9-CH2CH2COOH; mPEG10-acid; 2,5,8,11,14,17,20,23,26,29-Decaoxadotriacontan-32-oic acid |
IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
Canonical SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
InChI | InChI=1S/C22H44O12/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-22(23)24/h2-21H2,1H3,(H,23,24) |
InChIKey | DWDMPMQTMMOYQC-UHFFFAOYSA-N |
Boiling Point | 568.3±50.0°C at 760 mmHg |
Purity | >98% |
Density | 1.1±0.1 g/cm3 |
Solubility | 10 mm in DMSO |
Appearance | Pale Yellow or Colorless Oily Liquid |
Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
Storage | Store at 2-8°C |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
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- Introduction of Polyethylene Glycol (PEG)
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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