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mPEG4-amine
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| Category | Small-molecule Methoxy Linear PEG (mPEG) |
| Catalog NO. | BPG-1755 |
| Product Name | mPEG4-amine |
| CAS | 85030-56-4 |
| Molecular Formula | C9H21NO4 |
| Molecular Weight | 207.27 |
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| Description | m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | m-PEG4-amine; 3,6,9,12-Tetraoxatridecylamine; 2,5,8,11-Tetraoxatridecan-13-amine; mPEG4-NH2; 3,6,9,12-Tetraoxatridecanamine; Methyl-PEG4-Amine; Triethylene glycol 2-aminoethyl methyl ether; 3,6,9,12-Tetraoxatridecane-1-amine |
| IUPAC Name | 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanamine |
| Canonical SMILES | COCCOCCOCCOCCN |
| InChI | InChI=1S/C9H21NO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-10H2,1H3 |
| InChIKey | DQTQYVYXIOQYGN-UHFFFAOYSA-N |
| Boiling Point | 276.7±25.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.005±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| Related CAS | 80506-64-5 (polymer) 869718-87-6 (polymer) |
| Appearance | Colorless to almost colorless clear liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 207.14705815 |
| LogP | 0.34160 |
| Pictogram(s) | Corrosive |
| Signal | Danger |
| Precautionary Statement Codes | P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 |
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Technical Information
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Industry News
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- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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Improved Circulation Half-Life
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