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mPEG24-propionic acid

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Category Small-molecule Methoxy Linear PEG (mPEG)
Catalog NO. BPG-2637
Product Name mPEG24-propionic acid
CAS 125220-94-2
Molecular Formula C26H52O14
Molecular Weight 588.68
mPEG24-propionic acid
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Description mPEG11-propionic Acid (CAS# 125220-94-2) is a useful research chemical.
Synonyms 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
IUPAC Name 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI InChI=1S/C52H104O27/c1-55-4-5-57-8-9-59-12-13-61-16-17-63-20-21-65-24-25-67-28-29-69-32-33-71-36-37-73-40-41-75-44-45-77-48-49-79-51-50-78-47-46-76-43-42-74-39-38-72-35-34-70-31-30-68-27-26-66-23-22-64-19-18-62-15-14-60-11-10-58-7-6-56-3-2-52(53)54/h2-51H2,1H3,(H,53,54)
InChIKey RKDVSVRODIIQGU-UHFFFAOYSA-N
Boiling Point 628.8±55.0 °C at 760 mmHg
Purity >95%
Density 1.1±0.1 g/cm3
Appearance White Solid
Storage Store at 2-8°C
Exact Mass 588.33570633
LogP 0.12410

mPEG24-propionic acid, a versatile polymer compound renowned for its biocompatibility and customizable functionality, finds widespread utilization in various scientific and industrial settings. Here are four key applications of mPEG24-propionic acid, presented with elevated perplexity and burstiness:

Drug Delivery Systems: Within the realm of pharmaceuticals, mPEG24-propionic acid plays a crucial role in enhancing drug delivery systems by improving the solubility, stability, and bioavailability of therapeutic agents. Through the conjugation of drugs with mPEG24-propionic acid, researchers prolong their circulation time in the bloodstream and mitigate immunogenic responses. This versatile polymer facilitates the targeted and controlled release of active pharmaceutical ingredients, elevating the precision and efficacy of drug delivery mechanisms.

Protein Modification: In the dynamic arena of protein therapeutics, mPEG24-propionic acid shines as a pivotal tool for protein modification through a process known as PEGylation. This modification shields therapeutic proteins from enzymatic degradation and immune recognition, ensuring sustained therapeutic activity over prolonged durations. By leveraging mPEG24-propionic acid for PEGylation, the dosing frequency of therapeutic proteins is reduced, amplifying their effectiveness and longevity in combating various ailments.

Medical Device Coatings: Embracing innovation in medical technology, mPEG24-propionic acid emerges as a prominent choice for enhancing the biocompatibility of medical devices through specialized coatings. Coating implants, catheters, and other devices with this polymer diminishes protein adsorption and cellular adherence, thus lowering the risks of infection and immune responses. Such applications of mPEG24-propionic acid guarantee optimal functionality and integration of medical devices within the intricate environment of the human body.

Cosmetic Formulations: Within the cosmetic industry, mPEG24-propionic acid lends its prowess to formulations aimed at enhancing texture, stability, and efficacy of products. Its hydrophilic properties assist in moisturizing and soothing the skin, elevating the appeal and effectiveness of cosmetics. Additionally, mPEG24-propionic acid aids in the uniform dispersion of active ingredients, ensuring consistent application and superior performance of cosmetic products. By incorporating this polymer compound, cosmetic formulations are imbued with enhanced properties, catering to diverse consumer needs and preferences.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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