mPEG24-propionic acid
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Category | Small-molecule Methoxy Linear PEG (mPEG) |
Catalog NO. | BPG-2637 |
Product Name | mPEG24-propionic acid |
CAS | 125220-94-2 |
Molecular Formula | C26H52O14 |
Molecular Weight | 588.68 |
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Description | mPEG11-propionic Acid (CAS# 125220-94-2) is a useful research chemical. |
Synonyms | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
Canonical SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
InChI | InChI=1S/C52H104O27/c1-55-4-5-57-8-9-59-12-13-61-16-17-63-20-21-65-24-25-67-28-29-69-32-33-71-36-37-73-40-41-75-44-45-77-48-49-79-51-50-78-47-46-76-43-42-74-39-38-72-35-34-70-31-30-68-27-26-66-23-22-64-19-18-62-15-14-60-11-10-58-7-6-56-3-2-52(53)54/h2-51H2,1H3,(H,53,54) |
InChIKey | RKDVSVRODIIQGU-UHFFFAOYSA-N |
Boiling Point | 628.8±55.0 °C at 760 mmHg |
Purity | >95% |
Density | 1.1±0.1 g/cm3 |
Appearance | White Solid |
Storage | Store at 2-8°C |
Exact Mass | 588.33570633 |
LogP | 0.12410 |
mPEG24-propionic acid, a versatile polymer compound renowned for its biocompatibility and customizable functionality, finds widespread utilization in various scientific and industrial settings. Here are four key applications of mPEG24-propionic acid, presented with elevated perplexity and burstiness: Drug Delivery Systems: Within the realm of pharmaceuticals, mPEG24-propionic acid plays a crucial role in enhancing drug delivery systems by improving the solubility, stability, and bioavailability of therapeutic agents. Through the conjugation of drugs with mPEG24-propionic acid, researchers prolong their circulation time in the bloodstream and mitigate immunogenic responses. This versatile polymer facilitates the targeted and controlled release of active pharmaceutical ingredients, elevating the precision and efficacy of drug delivery mechanisms. Protein Modification: In the dynamic arena of protein therapeutics, mPEG24-propionic acid shines as a pivotal tool for protein modification through a process known as PEGylation. This modification shields therapeutic proteins from enzymatic degradation and immune recognition, ensuring sustained therapeutic activity over prolonged durations. By leveraging mPEG24-propionic acid for PEGylation, the dosing frequency of therapeutic proteins is reduced, amplifying their effectiveness and longevity in combating various ailments. Medical Device Coatings: Embracing innovation in medical technology, mPEG24-propionic acid emerges as a prominent choice for enhancing the biocompatibility of medical devices through specialized coatings. Coating implants, catheters, and other devices with this polymer diminishes protein adsorption and cellular adherence, thus lowering the risks of infection and immune responses. Such applications of mPEG24-propionic acid guarantee optimal functionality and integration of medical devices within the intricate environment of the human body. Cosmetic Formulations: Within the cosmetic industry, mPEG24-propionic acid lends its prowess to formulations aimed at enhancing texture, stability, and efficacy of products. Its hydrophilic properties assist in moisturizing and soothing the skin, elevating the appeal and effectiveness of cosmetics. Additionally, mPEG24-propionic acid aids in the uniform dispersion of active ingredients, ensuring consistent application and superior performance of cosmetic products. By incorporating this polymer compound, cosmetic formulations are imbued with enhanced properties, catering to diverse consumer needs and preferences. |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
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- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
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- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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