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mPEG2-amine
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| Category | Small-molecule Methoxy Linear PEG (mPEG) |
| Catalog NO. | BPG-1699 |
| Product Name | mPEG2-amine |
| CAS | 31576-51-9 |
| Molecular Formula | C5H13NO2 |
| Molecular Weight | 119.16 |
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| Description | m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | m-PEG2-amine; 1-(2-aminoethoxy)-2-methoxyethane; mPEG2-NH2; Ethanamine, 2-(2-methoxyethoxy)-; 2-(2-methoxyethoxy)ethan-1-amine; NH2-PEG2-OME; MeO-PEG(2)-NH2 |
| IUPAC Name | 2-(2-methoxyethoxy)ethanamine |
| Canonical SMILES | COCCOCCN |
| InChI | InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3 |
| InChIKey | QWCGXANSAOXRFE-UHFFFAOYSA-N |
| Boiling Point | 163.7±15.0 °C at 760 mmHg |
| Flash Point | 54.1±27.7 °C |
| Purity | ≥95% |
| Density | 0.934±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Related CAS | 80506-64-5 (polymer) 869718-87-6 (polymer) |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
| Exact Mass | 119.094628657 |
| Vapor Pressure | 2.0±0.3 mmHg at 25°C |
| LogP | -1.01 |
| Pictogram(s) | Corrosive, Acute Toxic, Irritant |
| Signal | Danger |
| Precautionary Statement Codes | P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
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- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
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- PEG Purification Techniques of Plasmid DNA
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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