mPEG11-alcohol

mPEG11-alcohol is a polyethylene glycol derivative with applications in various scientific and industrial fields. Here are some key applications of mPEG11-alcohol:

Drug Delivery Systems: mPEG11-alcohol is used to modify drug molecules to improve their solubility and stability. By attaching mPEG11-alcohol to pharmaceuticals, researchers can enhance drug bioavailability and prolong circulation time in the body. This technique is particularly useful for creating more effective and well-tolerated therapeutic formulations.

Bioconjugation: mPEG11-alcohol is employed in bioconjugation processes to link proteins, peptides, or other biomolecules. This helps in improving the pharmacokinetic properties of biologics and reducing immunogenicity. It is often used in the development of antibody-drug conjugates and other targeted therapies.

Surface Coatings: mPEG11-alcohol is applied in creating non-fouling surfaces, which are resistant to protein adsorption and cell attachment. This is critical in medical devices and implants to reduce the risk of infection and increase biocompatibility. Such coatings are also useful in biosensors and lab-on-chip devices to maintain sensor accuracy and efficiency.

Nanoparticle Stabilization: mPEG11-alcohol is utilized to coat and stabilize nanoparticles used in drug delivery and diagnostic imaging. By providing a hydrophilic barrier around nanoparticles, it prevents aggregation and enhances dispersion in biological environments. This leads to improved targeting and reduced clearance by the immune system, optimizing the efficacy of nanoparticle-based applications.