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mPEG10-amine

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Category Small-molecule Methoxy Linear PEG (mPEG)
Catalog NO. BPG-2216
Product Name mPEG10-amine
CAS 1383658-09-0
Molecular Formula C21H45NO10
Molecular Weight 471.58
mPEG10-amine
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Product Information

Description m-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Synonyms m-PEG10-amine; mPEG10-NH2; 2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-amine; 3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI InChI=1S/C21H45NO10/c1-23-4-5-25-8-9-27-12-13-29-16-17-31-20-21-32-19-18-30-15-14-28-11-10-26-7-6-24-3-2-22/h2-22H2,1H3
InChIKey JVILNPVFPORAFH-UHFFFAOYSA-N
Boiling Point 518.9±45.0 °C at 760 mmHg
Flash Point 254.4±22.4 °C
Purity ≥95%
Density 1.065±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO (10 mm)
Related CAS 80506-64-5 (polymer) 869718-87-6 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C
Exact Mass 471.30434663
Vapor Pressure 0.0±1.4 mmHg at 25°C
LogP -3.88

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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