Mal-Ph-CONH-PEG12-NHS ester
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| Category | Mal-Ph-CONH-PEGn-NHS ester |
| Catalog NO. | BPG-0423 |
| Product Name | Mal-Ph-CONH-PEG12-NHS ester |
| Molecular Formula | C42H63N3O19 |
| Molecular Weight | 913.97 |
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| Description | Mal-Ph-CONH-PEG12-NHS ester is a non-cleavable 12-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs). |
| Synonyms | 2,5-dioxopyrrolidin-1-yl 1-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32,35,38-dodecaoxa-2-azahentetracontan-41-oate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[3-(2,5-dioxopyrrol-1-yl)benzoyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O |
| InChI | InChI=1S/C42H63N3O19/c46-37-4-5-38(47)44(37)36-3-1-2-35(34-36)42(51)43-9-11-53-13-15-55-17-19-57-21-23-59-25-27-61-29-31-63-33-32-62-30-28-60-26-24-58-22-20-56-18-16-54-14-12-52-10-8-41(50)64-45-39(48)6-7-40(45)49/h1-5,34H,6-33H2,(H,43,51) |
| InChIKey | CDMJZMXUVSGHMS-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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Improved Circulation Half-Life
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