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Mal-PEG8-acid

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Category	Mal-PEGn-acid
Catalog NO.	BPG-0350
Product Name	Mal-PEG8-acid
CAS	1818294-46-0
Molecular Formula	C23H39NO12
Molecular Weight	521.56

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Description	Mal-PEG8-acid is a non-cleavable 8-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
Synonyms	Mal-PEG8-CH2CH2COOH; Maleimide-PEG8-CH2CH2COOH; Mal-PEG8-COOH; Mal-PEG8-propionic acid; 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid; 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-; 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
IUPAC Name	3-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	C1=CC(=O)N(C1=O)CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C23H39NO12/c25-21-1-2-22(26)24(21)4-6-30-8-10-32-12-14-34-16-18-36-20-19-35-17-15-33-13-11-31-9-7-29-5-3-23(27)28/h1-2H,3-20H2,(H,27,28)
InChIKey	KLZPPWOSICDUKQ-UHFFFAOYSA-N
Boiling Point	634.6±55.0°C at 760 mmHg
Purity	≥95%
Density	1.2±0.1 g/cm3
Solubility	Soluble in DCM, DMF, DMSO, Water
Related CAS	357277-61-3 (polymer) 2422928-26-3 (polymer)
Appearance	Light Yellow or White Solid
Storage	Store at 2-8°C

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