| Category | Mal-PEGn-PFP ester |
| Molecular Formula | C23H26F5NO9 |
| Molecular Weight | 555.45 |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) |
Mal-PEG5-PFP ester
Mal-PEG5-PFP ester is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.
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- Specification
| Synonyms | Mal-PEG5-PFP; 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester; Perfluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate; 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester |
| IUPACName | (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| CanonicalSMILES | C1=CC(=O)N(C1=O)CCOCCOCCOCCOCCOCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F |
| InChI | InChI=1S/C23H26F5NO9/c24-18-19(25)21(27)23(22(28)20(18)26)38-17(32)3-5-33-7-9-35-11-13-37-14-12-36-10-8-34-6-4-29-15(30)1-2-16(29)31/h1-2H,3-14H2 |
| InChIKey | HVQHYQSUANAJJW-UHFFFAOYSA-N |
| BoilingPoint | 594.2±50.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.376±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO |
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