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Mal-PEG5-NHS ester

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Category Mal-PEGn-NHS ester
Catalog NO. BPG-0368
Product Name Mal-PEG5-NHS ester
CAS 1807537-42-3
Molecular Formula C21H30N2O11
Molecular Weight 486.47
Mal-PEG5-NHS ester
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Product Information

Description Mal-PEG5-NHS ester is a non-cleavable ADC linker containing the Maleimide group. It can be used to prepare antibody conjugated drugs (ADCs).
Synonyms Mal-PEG5-NHS; 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate; 1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-[18-[(2,5-dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl]-
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCN2C(=O)C=CC2=O
InChI InChI=1S/C21H30N2O11/c24-17-1-2-18(25)22(17)6-8-30-10-12-32-14-16-33-15-13-31-11-9-29-7-5-21(28)34-23-19(26)3-4-20(23)27/h1-2H,3-16H2
InChIKey PDFXZGGPCFZXJU-UHFFFAOYSA-N
Boiling Point 608.4±65.0°C at 760 mmHg
Purity ≥95%
Density 1.3±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO
Related CAS 357277-60-2 (polymer) 1303508-68-0 (polymer) 1520853-90-0 (polymer) 1802486-72-1 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

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