| Category | Mal-amido-PEGn-TFP ester |
| Molecular Formula | C32H44F4N2O13 |
| Molecular Weight | 740.69 |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) |
Mal-amido-PEG8-TFP ester
Mal-amido-PEG8-TFP ester is a PEG linker containing a maleimide and TFP ester end group. The Maleimide group is reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chain increases the water solubility of a compound in aqueous media.
Structure of 1924596-31-5
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- Specification
| Synonyms | Mal-NH-PEG8-TFP; MAL-PEG8-TFP ester; MAL-dPEG8-TFP ester; 2,3,5,6-Tetrafluorophenyl 31-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontan-1-oate; 4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,3,5,6-tetrafluorophenyl ester; 2,3,5,6-tetrafluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oate |
| IUPACName | (2,3,5,6-tetrafluorophenyl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| CanonicalSMILES | C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC2=C(C(=CC(=C2F)F)F)F |
| InChI | InChI=1S/C32H44F4N2O13/c33-24-23-25(34)31(36)32(30(24)35)51-29(42)4-7-43-9-11-45-13-15-47-17-19-49-21-22-50-20-18-48-16-14-46-12-10-44-8-5-37-26(39)3-6-38-27(40)1-2-28(38)41/h1-2,23H,3-22H2,(H,37,39) |
| InChIKey | YQFZOPSEPCSFQQ-UHFFFAOYSA-N |
| BoilingPoint | 780.6±60.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.3±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
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