Mal-amido-PEG6-CH2CH2COOPFP ester

Name: Mal-amido-PEG6-CH2CH2COOPFP ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 1599432-34-4

Cat No.: BPG-2460

Purity: >97%

4.5

Mal-NH-PEG6-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based PROTAC linker. Mal-NH-PEG6-CH2CH2COOPFP ester can be used in the synthesis of a series of PROTACs.

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C₂₈H₃₅F₅N₂O₁₁
Molecular Weight	670.58
Appearance	Viscous Liquid
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Structure of 1599432-34-4

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Maleimide-NH-PEG6-CH2CH2COOPFP ester; Mal-NH-PEG6-CH2CH2COOPFP ester
IUPACName	(2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F
InChI	InChI=1S/C28H35F5N2O11/c29-23-24(30)26(32)28(27(33)25(23)31)46-22(39)4-7-40-9-11-42-13-15-44-17-18-45-16-14-43-12-10-41-8-5-34-19(36)3-6-35-20(37)1-2-21(35)38/h1-2H,3-18H2,(H,34,36)
InChIKey	PELJIWMJFINXNE-UHFFFAOYSA-N
Purity	>97%
Density	1.3±0.1 g/cm3

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Monofunctional (Reactive)

ReactiveToward	Thiols; Primary Amines
ReactionChemistry	Maleimide-Thiol Conjugation; Activated-Ester Amine Coupling
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Amine-Selective Biomolecule Coupling; Thiol-Selective Biomolecule Conjugation