Hydroxy-PEG4-t-butyl ester

Name: Hydroxy-PEG4-t-butyl ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 518044-32-1

Cat No.: BPG-1956

Purity: ≥95%

4.5

Hydroxy-PEG4-t-butyl ester is a protected PEG linker intermediate used in ADC synthesis. The t-butyl group protects the acid functionality, enabling selective conjugation steps while the PEG4 spacer enhances biocompatibility and payload solubility.

Category	HO-PEGn-COOtBu
Molecular Formula	C15H30O7
Molecular Weight	322.39
Appearance	Colorless to light yellow to light orange clear liquid
Shipping	Room temperature, or blue ice upon request.
Storage	Store at 2-8°C

Structure of 518044-32-1

Ordering Information

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Specification

Synonyms	HO-PEG4-CH2CH2COOtBu; Hydroxy-PEG4-(CH2)2-Boc; OH-PEG4-TBA; OH-PEG4-CH2CH2COOtBu; HO-PEG4-t-butyl ester; tert-Butyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate; 15-Hydroxy-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester; 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate; 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester
IUPACName	tert-butyl 3-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	CC(C)(C)OC(=O)CCOCCOCCOCCOCCO
InChI	InChI=1S/C15H30O7/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h16H,4-13H2,1-3H3
InChIKey	FJRDXEGYAVAMLB-UHFFFAOYSA-N
BoilingPoint	406.8±35.0 °C at 760 mmHg
Purity	≥95%
Density	1.047±0.1 g/cm3
Solubility	Soluble in DCM, DMSO, Water
RelatedCAS	1186025-29-5 (polymer) 892154-71-1 (polymer)
ExactMass	322.19915329
LogP	0.77690
Pictogram	Irritant
Signal	Warning
PrecautionaryStatementCodes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501