Hydroxy-PEG4-t-butyl ester
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Category | Small-molecule Group Protected PEG |
Catalog NO. | BPG-1956 |
Product Name | Hydroxy-PEG4-t-butyl ester |
CAS | 518044-32-1 |
Molecular Formula | C15H30O7 |
Molecular Weight | 322.39 |
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Description | Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). |
Synonyms | HO-PEG4-CH2CH2COOtBu; Hydroxy-PEG4-(CH2)2-Boc; OH-PEG4-TBA; OH-PEG4-CH2CH2COOtBu; HO-PEG4-t-butyl ester; tert-Butyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate; 15-Hydroxy-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester; 2-Methyl-2-propanyl 1-hydroxy-3,6,9,12-tetraoxapentadecan-15-oate; 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy-, 1,1-dimethylethyl ester |
IUPAC Name | tert-butyl 3-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoate |
Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCO |
InChI | InChI=1S/C15H30O7/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h16H,4-13H2,1-3H3 |
InChIKey | FJRDXEGYAVAMLB-UHFFFAOYSA-N |
Boiling Point | 406.8±35.0 °C at 760 mmHg |
Purity | ≥95% |
Density | 1.047±0.1 g/cm3 |
Solubility | Soluble in DCM, DMSO, Water |
Related CAS | 1186025-29-5 (polymer) 892154-71-1 (polymer) |
Appearance | Colorless to light yellow to light orange clear liquid |
Storage | Store at 2-8°C |
Exact Mass | 322.19915329 |
LogP | 0.77690 |
Pictogram(s) | Irritant |
Signal | Warning |
Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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