Hydroxy-PEG3-C2-PFP ester
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| Category | HO-PEGn-C2-PFP ester |
| Catalog NO. | BPG-0619 |
| Product Name | Hydroxy-PEG3-C2-PFP ester |
| CAS | 1807537-40-1 |
| Molecular Formula | C15H17F5O6 |
| Molecular Weight | 388.28 |
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Product Information
| Description | Hydroxy-PEG3-C2-PFP ester is a PEG linker containing a hydroxyl group with a PFP ester group. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PFP esters have similar applications as the NHS esters but are more stable in aqueous solution. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. |
| Synonyms | Hydroxy-PEG3-PFP ester; Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester; Pentafluorophenyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate |
| IUPAC Name | (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate |
| SMILES | C(COCCOCCOCCO)C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F |
| InChI | InChI=1S/C15H17F5O6/c16-10-11(17)13(19)15(14(20)12(10)18)26-9(22)1-3-23-5-7-25-8-6-24-4-2-21/h21H,1-8H2 |
| InChIKey | MDIKFXKPNIRFLO-UHFFFAOYSA-N |
| Boiling Point | 440.3±45.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Storage | Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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Improved Circulation Half-Life
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