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Fmoc-N-amido-PEG8-acetic acid

CAS No. CAS No.: 868594-52-9
Cat No. Cat No.: BPG-2443
Purity Purity: >98.0%
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Fmoc-N-amido-PEG8-acetic acid acts as a protective group-containing ADC linker intermediate, enhancing conjugation flexibility and solubility in antibody-drug conjugates for precise drug delivery.

Category Fmoc-NH-PEGn-CH2COOH
Molecular Formula C33H47NO12
Molecular Weight 649.73
Appearance Pale Yellow Oily Matter
Shipping Room temperature
Storage Store at -20°C, keep in dry and avoid sunlight
Fmoc-N-amido-PEG8-acetic acid

Structure of 868594-52-9

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  • Specification
Synonyms Fmoc-NH-PEG8-CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid; Fmoc-PEG8-acetic acid; 26-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15,18,21,24-octaoxahexacosanoic acid; 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-NH-8(ethylene glycol)-acetic acid; 2,7,10,13,16,19,22,25,28-Nonaoxa-4-azatriacontan-30-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
IUPACName 2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CanonicalSMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)O
InChI InChI=1S/C33H47NO12/c35-32(36)26-45-24-23-44-22-21-43-20-19-42-18-17-41-16-15-40-14-13-39-12-11-38-10-9-34-33(37)46-25-31-29-7-3-1-5-27(29)28-6-2-4-8-30(28)31/h1-8,31H,9-26H2,(H,34,37)(H,35,36)
InChIKey JRLUSGRARXJCNA-UHFFFAOYSA-N
BoilingPoint 773.7±60.0°C (Predicted)
Purity >98.0%
Density 1.201±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO (10 mm)
RelatedCAS 675606-79-8 (polymer)
ShelfLife 0-4°C for short term (days to weeks), or -20°C for long term (months).
LogP 3.13340

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