Fmoc-N-amido-PEG4-acetic acid

Name: Fmoc-N-amido-PEG4-acetic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 437655-95-3

Cat No.: BPG-2219

Purity: ≥95%

4.5

Fmoc-N-amido-PEG4-acetic acid is a PEG linker intermediate with an Fmoc protecting group, used for stepwise ADC linker synthesis. The PEG4 spacer improves hydrophilicity and flexibility, aiding in controlled payload conjugation and antibody modification.

Category	Fmoc-NH-PEGn-CH2COOH
Molecular Formula	C25H31NO8
Molecular Weight	473.52
Appearance	Pale Yellow or Colorless Oily Matter
Shipping	Room temperature
Storage	Store at 2-8°C

Structure of 437655-95-3

Ordering Information

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Specification

Synonyms	Fmoc-NH-PEG4-CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid; 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-PEG4-acetic acid; 2,7,10,13,16-Pentaoxa-4-azaoctadecan-18-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
IUPACName	2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CanonicalSMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCC(=O)O
InChI	InChI=1S/C25H31NO8/c27-24(28)18-33-16-15-32-14-13-31-12-11-30-10-9-26-25(29)34-17-23-21-7-3-1-5-19(21)20-6-2-4-8-22(20)23/h1-8,23H,9-18H2,(H,26,29)(H,27,28)
InChIKey	XPNLDOFYRFOXLR-UHFFFAOYSA-N
BoilingPoint	681.3±55.0°C (Predicted)
MeltingPoint	51°C
Purity	≥95%
Density	1.235±0.06 g/cm3 (Predicted)
Solubility	Soluble in DMSO (10 mm)
RelatedCAS	675606-79-8 (polymer)
ExactMass	473.20496695
LogP	2.88050