| Category | mPEG Phospholipids |
| Molecular Formula | (C2H4O)nC44H83N2O10P.H3N |
| Molecular Weight | 2786.489 |
| Storage | Store at -20°C |
DOPE-PEG-NH2 ammonium salt
DOPE-PEG-NH2 ammonium salt features a terminal amine group on a PEGylated phosphatidylethanolamine backbone, providing a reactive platform for further chemical modification. The primary amine moiety enables facile coupling with activated esters, aldehydes, or carboxyl groups, facilitating the creation of diverse lipid conjugates. The DOPE anchor maintains membrane fluidity and curvature, while the PEG segment enhances solubility and biocompatibility. As an ammonium salt, it offers improved handling and aqueous dispersibility. DOPE-PEG-NH2 is frequently employed in customizable liposome construction, polymer grafting, and the generation of multifunctional lipid nanostructures with controlled surface chemistry.
Structure of 2342575-85-1
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- Specification
| Synonyms | DOPE-PEG-Amine ammonium salt; DOPE-PEG-NH2; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)]; Poly(oxy-1,2-ethanediyl), α-[(9R,20Z)-6-hydroxy-6-oxido-1,12-dioxo-9-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-5,7,11-trioxa-2-aza-6-phospha-20-nonacosen-1-yl]-ω-(2-aminoethoxy)-, ammonium salt |
| Purity | >99% |
| Solubility | Soluble in Chloroform, Methanol, Ammonium Hydroxide |
| RelatedCAS | 1429661-98-2 (free base) |
| ShelfLife | 1 Year |
| ExactMass | 2784.759 |
| Hygroscopic | No |
| LightSensitive | No |
| PercentComposition | C 56.90%, H 9.48%, N 1.51%, O 31.00%, P 1.11% |
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