Desthiobiotin-PEG3-NHS ester

Name: Desthiobiotin-PEG3-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 2411681-92-8

Cat No.: BPG-4491

Purity: 0.95

4.5

Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Please contact us for GMP-grade inquiries.

Category	Small-molecule Biotin PEG
Molecular Formula	C23H38N4O9
Molecular Weight	514.6
Shipping	Ambient temperature
Storage	-20°C

Structure of 2411681-92-8

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Specification

Synonyms	Desthiobiotin-PEG3-NHS ester; BP-24457; CS-0254600; 2411681-92-8; Rel-2,5-dioxopyrrolidin-1-yl 19-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-14-oxo-4,7,10-trioxa-13-azanonadecanoate
IUPACName	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	CC1C(NC(=O)N1)CCCCCC(=O)NCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI	InChI=1S/C23H38N4O9/c1-17-18(26-23(32)25-17)5-3-2-4-6-19(28)24-10-12-34-14-16-35-15-13-33-11-9-22(31)36-27-20(29)7-8-21(27)30/h17-18H,2-16H2,1H3,(H,24,28)(H2,25,26,32)/t17-,18+/m0/s1
InChIKey	JWHMGEZINQQWSX-ZWKOTPCHSA-N
Purity	0.95