Cl-PEG7-acid
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Category | Cl-PEGn-acid |
Catalog NO. | BPG-1534 |
Product Name | Cl-PEG7-acid |
Molecular Formula | C17H33ClO9 |
Molecular Weight | 416.89 |
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Synonyms | Cl-PEG7-CH2CH2COOH; 1-chloro-3,6,9,12,15,18,21-heptaoxatetracosan-24-oic acid |
IUPAC Name | 3-[2-[2-[2-[2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCCl |
InChI | InChI=1S/C17H33ClO9/c18-2-4-22-6-8-24-10-12-26-14-16-27-15-13-25-11-9-23-7-5-21-3-1-17(19)20/h1-16H2,(H,19,20) |
InChIKey | KYOFCFKPCVLWFT-UHFFFAOYSA-N |
Purity | ≥95% |
Storage | Store at 2-8°C |
Cl-PEG7-acid, a versatile chemical compound widely employed in various bioscience applications, boasts a myriad of uses. Here are four key applications: Drug Delivery Systems: Embedded in the realm of drug delivery systems, Cl-PEG7-acid plays a pivotal role in enhancing drug solubility and stability. By conjugating with pharmaceuticals, it elevates their bioavailability and therapeutic effectiveness, facilitating the precise delivery of drugs to their intended targets within the body. This synergy ensures a more efficient and targeted drug delivery mechanism. Bioconjugation: The reactive Cl group within Cl-PEG7-acid lends itself to bioconjugation endeavors, where it acts as a bridge linking biomolecules like proteins, peptides, and antibodies with other chemical entities. This intricate conjugation process is indispensable in the creation of labeled probes, imaging agents, and therapeutic conjugates. By bolstering the stability and functionality of biomolecules, Cl-PEG7-acid amplifies their utility in both diagnostic and therapeutic realms, unveiling new possibilities in bioconjugation technologies. Surface Modification: Engaged in the domain of surface modification, Cl-PEG7-acid serves as a cornerstone for crafting biocompatible and non-fouling surfaces. Through the grafting of Cl-PEG7-acid onto surfaces, researchers can thwart the nonspecific binding of proteins and cells, a critical facet in the development of cutting-edge biomedical devices and biosensors. This application is paramount in ensuring the enduring performance and reliability of medical implants and diagnostic tools. Polymer Chemistry: Within polymer chemistry, Cl-PEG7-acid emerges as a vital building block, instrumental in synthesizing PEGylated polymers endowed with tailored properties. These polymers find utility in the creation of hydrogels, nanoparticles, and diverse materials for both biomedical and industrial applications. The incorporation of Cl-PEG7-acid offers meticulous control over polymer architecture and functionality, resulting in superior material performance across various applications in polymer chemistry. |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
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- PEG for Drug Delivery
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- PEG Purification Techniques of Plasmid DNA
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- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
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Industry News
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- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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