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CHO-Ph-CONH-PEG1-azide

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Category CHO-Ph-CONH-PEGn-azide
Catalog NO. BPG-0919
Product Name CHO-Ph-CONH-PEG1-azide
Molecular Formula C12H14N4O3
Molecular Weight 262.27
CHO-Ph-CONH-PEG1-azide
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Product Information

Description CHO-Ph-CONH-PEG1-azide is a PEG reagent containing a benzaldehyde group and a terminal azide group. The benzaldehyde can react with primary amines. The azide can react with alkynes, DBCO and BCN moieties via Click Chemistry reactions.
Synonyms Ald-Ph-PEG1-Azide; DF-PEG1-N3; Ald-Ph-amido-C2-PEG1-azide; Ald-Ph-PEG1-N3; CHO-Ph-PEG1-azide
IUPAC Name N-[2-(2-azidoethoxy)ethyl]-4-formylbenzamide
Canonical SMILES O=C(NCCOCCN=[N+]=[N-])C1=CC=C(C=O)C=C1
InChI InChI=1S/C12H14N4O3/c13-16-15-6-8-19-7-5-14-12(18)11-3-1-10(9-17)2-4-11/h1-4,9H,5-8H2,(H,14,18)
InChIKey QUCRBGIATDDFGF-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C

CHO-Ph-CONH-PEG1-azide, a versatile chemical linker with wide-ranging applications in biomedical and chemical fields, plays a pivotal role in various cutting-edge applications. Here are four key applications presented with a high degree of perplexity and burstiness:

Bioconjugation: Widely employed in bioconjugation techniques, CHO-Ph-CONH-PEG1-azide serves as a crucial tool for covalently linking biomolecules like proteins, peptides, or antibodies to diverse surfaces or molecules. The unique azide functional group facilitates participation in click chemistry reactions, enabling precise and efficient conjugation. This application is instrumental in driving the development of advanced diagnostic assays, biosensors, and therapeutic agents, propelling forward the boundaries of biotechnology and medical research.

Drug Delivery: Embracing the realm of drug delivery, CHO-Ph-CONH-PEG1-azide emerges as a game-changer for modifying drug molecules to achieve targeted delivery and controlled release. By enabling the attachment of drugs to carrier molecules like nanoparticles or liposomes, this compound enhances therapeutic efficacy while minimizing side effects. This intricate process ensures that drugs reach their intended site of action with precision.

Surface Modification: In the realm of material science and biomedical engineering, CHO-Ph-CONH-PEG1-azide plays a vital role in surface modification of diverse materials, including nanoparticles, medical devices, and implants. Facilitating PEGylation, this compound reduces protein adsorption and enhances biocompatibility, crucial for preventing immune responses and improving the performance and durability of biomedical devices.

Chemical Biology Research: An indispensable tool in the realm of chemical biology, CHO-Ph-CONH-PEG1-azide is leveraged for studying molecular interactions and pathways with unparalleled precision. By introducing this functional group into biomolecules, researchers can intricately control and monitor their behavior within biological systems, shedding light on complex biological mechanisms. This sophisticated approach empowers researchers to design new molecular probes, unravel intricate biological processes.

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