CbzNH-PEG2-CH2CH2NH2
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| Category | CbzNH-PEGn-CH2CH2NH2 |
| Catalog NO. | BPG-1448 |
| Product Name | CbzNH-PEG2-CH2CH2NH2 |
| CAS | 169744-02-9 |
| Molecular Formula | C14H22N2O4 |
| Molecular Weight | 282.34 |
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| Description | CbzNH-PEG2-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. |
| Synonyms | Benzyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; {2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester; 8-Amino-3,6-dioxaoctane-1-ylcarbamic acid benzyl ester; Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, phenylmethyl ester |
| IUPAC Name | benzyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate |
| Canonical SMILES | C1=CC=C(C=C1)COC(=O)NCCOCCOCCN |
| InChI | InChI=1S/C14H22N2O4/c15-6-8-18-10-11-19-9-7-16-14(17)20-12-13-4-2-1-3-5-13/h1-5H,6-12,15H2,(H,16,17) |
| InChIKey | RPEJOLSCRIIGNT-UHFFFAOYSA-N |
| Boiling Point | 442.8±40.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.129±0.06 g/cm3 (Predicted) |
| Storage | Store at 2-8°C |
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Technical Information
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Industry News
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
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