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C12-NBD Phytosphingosine

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Category	Extracts
Catalog NO.	BPG-3249
Product Name	C12-NBD Phytosphingosine
CAS	388566-94-7
Molecular Formula	C36H63N5O7
Molecular Weight	677.92

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Product Information

Description	C12-NBD Phytosphingosine is a fluorescent derivative of phytosphingosine. Phytosphingosine is a naturally occurring lipid compound localized in skin, kidney and intestines.
Synonyms	N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine
IUPAC Name	(2S,3S,4R)-2-aminooctadecane-1,3,4-triol
Canonical SMILES	CCCCCCCCCCCCCCC(C(C(CO)N)O)O
InChI	InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChIKey	AERBNCYCJBRYDG-KSZLIROESA-N
Melting Point	102 - 103 °C
Purity	>99%
Appearance	Powder
Shelf Life	1 Year
Storage	Store at -20°C
Hygroscopic	No
Light Sensitive	No
Percent Composition	C 63.78%, H 9.37%, N 10.33%, O 16.52%
Pictogram(s)	Corrosive, Environmental Hazard
Signal	Danger
Precautionary Statement Codes	P264+P265, P273, P280, P305+P354+P338, P317, P391, and P501

References

1. Gupta P, Roy S, Nandi AK. MEDEA-interacting protein LONG-CHAIN BASE KINASE 1 promotes pattern-triggered immunity in Arabidopsis thaliana. Plant Mol Biol. 2020 Feb 25. doi: 10.1007/s11103-020-00982-4. Epub ahead of print. PMID: 32100164. PubMed ID: 32100164.
2. Bae DJ, Seo J, Kim SY, Park SY, Do Yoo J, Pyo JH, Cho W, Cho JY, Kim S, Kim IS. ArhGAP12 plays dual roles in Stabilin-2 mediated efferocytosis: Regulates Rac1 basal activity and spatiotemporally turns off the Rac1 to orchestrate phagosome maturation. Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1595-1607. doi: 10.1016/j.bbamcr.2019.07.003. Epub 2019 Jul 10. PubMed ID: 31301364.
3. Takahashi M, Izawa K, Urai M, Yamanishi Y, Maehara A, Isobe M, Matsukawa T, Kaitani A, Takamori A, Uchida S, Yamada H, Nagamine M, Ando T, Shimizu T, Ogawa H, Okumura K, Kinjo Y, Kitamura T, Kitaura J. The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment. Sci Signal. 2019 Jan 15;12(564). pii: eaar5514. doi: 10.1126/scisignal.aar5514. PubMed ID: 30647146.

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