BrCH2CONH-PEG10-NHS ester
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| Category | BrCH2CONH-PEGn-NHS ester |
| Catalog NO. | BPG-1348 |
| Product Name | BrCH2CONH-PEG10-NHS ester |
| Molecular Formula | C29H51BrN2O15 |
| Molecular Weight | 747.63 |
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Product Information
| Description | BrCH2CONH-PEG10-NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
| Synonyms | Bromoacetamido-PEG10-C2-NHS ester; Bromoacetamido-PEG10-NHS ester; 2,5-dioxopyrrolidin-1-yl 1-bromo-2-oxo-6,9,12,15,18,21,24,27,30,33-decaoxa-3-azahexatriacontan-36-oate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CBr)=O |
| InChI | InChI=1S/C29H51BrN2O15/c30-25-26(33)31-4-6-38-8-10-40-12-14-42-16-18-44-20-22-46-24-23-45-21-19-43-17-15-41-13-11-39-9-7-37-5-3-29(36)47-32-27(34)1-2-28(32)35/h1-25H2,(H,31,33) |
| InChIKey | LUMZKHXHGABYEU-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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